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«The main objective of the different treatments for pelvic organ prolapse (POP) is focused on recomposing the woman’s anatomy to redirect the situation and, in turn, return normality to her altered bodily functions, such as urination, deposition or sexuality”, informs the urologist and surgeon, Carmen González Enguita.

The multidisciplinary treatment of POP women

“But we should not always go to treatment once the diagnosis has been established,” says the head of the Urology Service at the Fundación Jiménez Díaz University Hospital in Madrid. If women have no or mild symptoms, the emphasis should be on avoiding risk factors.”

“Even so, the specialists will carry out regular follow-up consultations to control the woman’s POP progression in detail,” he adds.

An organ prolapse is any descent into the pelvic floor or perineum of part of the bladder, uterus, rectum, including bowel loops, through the vagina. It is a frequent condition that up to 40% of multiparous mothers can suffer, that is, who have had several births.

In these surprising cases, the most important thing is that the multidisciplinary team virtuously demonstrate their knowledge of the anatomy and physiology of the pelvic floor.

“We must be sure of what is happening in the pelvic area for this vaginal descent of organs to occur and at the same time understand the pathophysiology of prolapse. Both aspects are fundamental when we have to plan the treatment».

“Furthermore, I would say that all women who consult for this POP problem, once diagnosed, need a preventive guidance so that they understand it well and can take care of themselves properlyavoiding factors that facilitate the progression of the pathology».

Dr. Carmen González Enguita explains pelvic organ prolapse-POP

We CANNOT avoid age, or past pregnancies, or complex deliveries, or perhaps that musculoskeletal weakness characteristic of each person, or the stages that women go through throughout their lives… but we CAN avoid all those situations that increase, inappropriately, abdominal pressure.

Obesity, constipation, lung pathology that leads to chronic cough, so you have to stop smoking, important efforts performed incorrectly, such as carrying or pushing weights, and impact sports.

However, it is usually advisable to maintain healthy physical exercise, as well as rehabilitate and strengthen the pelvic floor.

Dr. Carmen González Enguita

Rehabilitation and physiotherapy with Kegel and pessaries

«They make up a specialty within Physical Medicine, which is in charge of helping to know where the muscles of the perineum are, those that participate in these pelvic problems, to learn how to exercise them, train them and strengthen them to prevent prolapse, stop its advance or even push it back,” he says.

With the kegel exercises it is possible to firmly tighten the musculature that surrounds the vagina, the urethra and the rectum.

“We must contract the muscles for one or two seconds, approximately, and then relax them for ten seconds. Little by little, the contractions lengthen until they reach periods of ten seconds, thus equaling the relaxation time », he explains.

This exercise, which women can do sitting, standing or lying down, will be repeated about ten times in a row, recommending doing each series several times a day.

Women can also use vaginal cones: inserted into the vagina, they help to contract the correct muscles to prevent the cone from falling to the ground under its own weight”, she describes.

In Rehabilitation, they also work with biofeedback devices, sensors that show the muscle contractions of the pelvic floor on a screen, and electrical stimulation, with a probe to transmit current and contract the target muscle.

The pessaries They are circular devices, although there are different shapes and models, which are inserted into the vagina to support the pelvic organs.

“They reduce prolapse and reduce symptoms, but they are not a cure. They are especially beneficial for women who are waiting for surgery and for those who do not want or cannot undergo surgery, “says the urologist.

Pelvic organ prolapse-POP-

Anatomical reconstruction of the pelvic floor and the use of mesh

When pelvic floor rehabilitation does not achieve its goals, surgical intervention is necessary to definitively treat pelvic organ prolapse (POP).

“Surgery is used in those POP cases that cause an alteration in the patient’s quality of life, whether due to discomfort, pain, loss of urine, urination difficulty, constipation or problems in sexual relations,” he relates.

There are several types of interventions, most based on anatomical reconstruction of the pelvic floor. Always try to use the patient’s own tissues.

“When these tissues are very weak and in poor condition, or when we believe that the repair cannot be carried out with these tissues, we will use tissues designed and manufactured for this purpose, such as the well-known tights«, exposes.

Dr. Carmen González Enguita

Surgeries can be performed vaginally and/or abdominally. The decision of one or the other approach will depend on the type of prolapse, the anatomical characteristics of the patient, her age, her sexual life and the skills of the surgeon.

Pelvic organ prolapse-POP“There are many different types of surgeries and ways to perform them. In this section, the specialist should be consulted, with whom the best agreement will surely be reached, depending on both the POP problem and the patient’s preferences and values”, concludes Dr. Carmen González Enguita.

Recovery time will depend on the type of surgery. Most women will be able to gradually resume their physical activity in a few weeks, normality conditioned by the surgical technique used.

During the six months after the intervention to correct a pelvic organ prolapse (POP), straining or lifting heavy weights should be avoided, as they can affect healing.

The Hospital Clínic de Barcelona has shown that a change in the timing of administering a treatment that is already used to treat ischemic stroke increases the chances of the patient obtaining an excellent recovery and without sequelae three months after the procedure by up to 59%. .

This marks a before and after stroke treatment”, highlighted the Head of the Cerebral Vascular Pathology Unit of the Clínic, Ángel Chamorro, coordinator of the CHOICE study with results on the sequelae, which has been presented at the International Stroke Conference in New Orleans (United States) and has been published in the journal «JAMA».

Ischemic stroke, which represents 85% of all embolisms, is caused by the obstruction of a cerebral blood vessel and causes 6 million deaths each year in the world, being the second leading cause of death.

If it does not kill, the stroke can leave important consequences for life -in fact it is the first medical cause of disability in the world-, even in those patients who, mechanically, manage to extract the thrombus from the blood.

an intravenous drug

In the first 24 hours after the appearance of the stroke, the treatment consists of administering an intravenous drug, alteplase; and performing a mechanical thrombectomy, which consists of inserting a catheter through the artery until it reaches the thrombus, in order to extract it.

In 85% of cases it is possible to remove the thrombus and restore blood circulation in the brain, but this is not always a guarantee of complete recovery, since after 3 months many patients present sequelae or some type of disability.

The researchers of clinic and the August Pi i Sunyer Biomedical Research Institute (Idibaps) suspected that the problem could be that there was thrombosis in the capillary vessels, the “peripheral roads” of the bloodstream network, which can become as fine as a hair and of which it is not possible to have images.

Thus arose the CHOICE projectwhose objective was to test whether the same drug that is given in the first hours of the stroke, alteplase, could help reduce possible damage to the capillaries if administered after thrombectomy to remove the thrombus.

The study, financed with funds from the TV3 Marathon, had 121 participants, randomly divided into two groups: one was administered the drug after removing the thrombus and the second, placebo.

sequelae stroke treatment
Javier, a 51-year-old patient who is recovering from a stroke, performs a rehabilitation exercise to avoid sequelae at the Vall d’Hebron Hospital Neurorehabilitation Day Hospital, EFE/Toni Albir

The results of the CHOICE project

The results have demonstrated the efficacy of this change in treatment: in the placebo group, 40% of the patients remained without sequelae and with independent life, without disability, while among those who received the drug after thrombectomy the percentage it rose to 59%, a difference therefore of 19% between the two groups.

The advantage of this study is that the drug is already available in hospitals, so as of this Thursday there will be “many professionals in the world who will begin to do it,” Dr. Chamorro ventured.

In any case, for the most “skeptical”, he has considered that a second study will be necessary with a more “robust” sample of patients so that the new procedure is validated and can be included in the clinical guidelines, a process that could be completed between this year and the next, he estimated.

For its part, the neurologist at Clínic-IDIBAPS and coordinator of the clinical trial, Arturo Renú, has specified that, although they have shown a “better efficacy” of the drug “once the artery is opened”, this does not mean that it has to be stopped before thrombectomy, as is currently done: “Only if You have a little drug left after the first administration, save it because it will work very well later, “he advised.

María Barranco is one of the patients who was fortunate to emerge unscathed from the stroke he suffered a year ago: “I was lucky that Dr. Renú’s team took me in right away and now I’ve realized that I was luckier to be in the drug group.”

Citing “crimes against humanity and genocide” against the Uyghur Muslim minority in China’s Xinjiang province, the French Parliament on Thursday passed a non-binding motion urging French authorities to condemn Beijing.

The measure, which passed 169-1, was led by the Socialist and other opposition parties.

In addition to condemning China, the motion urges the government to protect France’s Uyghur immigrant community from harassment by China.

The Chinese Embassy in France called the move absurd and said it would harm relations between the two countries.

“The French side is fully aware of the absurdity and harmfulness of this resolution. It must show coherence between word and deed and take concrete actions to safeguard the healthy development of Sino-French relations,” the embassy said in a statement.

China is accused of carrying out genocide and forced labor against the province’s large Uyghur Muslim population. It denies the accusations.

The move comes on the eve of the 2022 Beijing Winter Olympics. Several western countries, including the United States, Britain and Australia have announced “diplomatic boycotts” of the games and will not send delegations to attend.

French President Emmanuel Macron in December questioned the effectiveness of such boycotts and said he didn’t want to “politicize” the games.

Last year, the Dutch Parliament passed a similar resolution which earned a sharp rebuke from Beijing. Italy and Belgium have condemned China over Xinjiang but did not use the term genocide.

Some information in this report comes from Reuters.

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